NFL Betting 2021 Regular Season Week 5 Predictions

NFL Betting: 2021 Regular Season Week 5 Predictions

Written by on October 5, 2021

We’ve arrived at Week 5 of the NFL season, and the early odds have been released. Here are our early-week predictions for the upcoming slate of games.

Los Angeles Rams @ Seattle Seahawks (-1)

This will be the Thursday Night Football game. Seattle is coming off of a big win over the Niners, while the Rams lost their first game of the season to the Arizona Cardinals. Every game in this division is crucial this season, as all four teams will be in the NFC playoff picture. We like the Rams to win this one outright.

New York Jets @ Atlanta Falcons (-3.5)

Even though this is a home game for the Falcons, the game will be played in London. The Jets won their first game of the year last Sunday, while the Falcons lost to the Washington Football Team. We’re going with the Jets in the upset.

Detroit Lions @ Minnesota Vikings (-8.5)

The powerful Vikings offense was only able to put up seven points in a loss to the Cleveland Browns. However, the Vikings’ defense that hadn’t played very well this season only gave up 14. Detroit looked awful against a bad Chicago Bears squad. We like Minnesota to win and cover.

Green Bay Packers @ Cincinnati Bengals (+3.5)

The Bengals are 3-1, but the victories have come over some of the softer teams in the league. Joe Burrow is playing well and looks like a future superstar. Aaron Rodgers was awful in the season opener, but since then he’s been great. Rodgers and the Packers will come into Cincinnati and beat the Bengals by a touchdown.

New Orleans Saints @ Washington Football Team (+1)

The New York Giants beat the Saints, while the WFT defeated the Atlanta Falcons. WFT’s defense was supposed to be one of the top units in the league, but they have yet to play that way. New Orleans has been inconsistent on offense. In a low-scoring affair, the WFT will beat the Saints.


Philadelphia Eagles @ Carolina Panthers (-4.5)

The Panthers are a different team without Christian McCaffrey. They were undefeated but lost on Sunday to the Cowboys. The Eagles couldn’t keep up with the high-powered Kansas City Chiefs. We like the Panthers to win this game, but they won’t cover the spread.

Tennessee Titans @ Jacksonville Jaguars (+4)

Derrick Henry will run wild over the Jaguars’ porous defense. Enough said. Tennessee wins this one easily.

Miami Dolphins @ Tampa Bay Buccaneers (-10)

Miami’s offense has been anemic this season. Their offensive line is weak, they’re playing with a backup quarterback, and they can’t figure out how to score. The Tampa Bay defensive line will take advantage of Miami’s O-line issues. Brady and the Bucs waltz all over the Dolphins and cover this large spread.

Denver Broncos @ Pittsburgh Steelers (Pick’ Em)

This one is up in the air due to the injury status of Teddy Bridgewater. Pittsburgh hasn’t looked good since Week 1. Denver’s defense will be too much for the aging Big Ben.

Chicago Bears @ Las Vegas Raiders (-5)

We don’t know who’ll be under center for the Bears, but we don’t think that it will matter. The raiders win by a touchdown.

Cleveland Browns @ Los Angeles Chargers (+1)

Justin Herbert and Baker Mayfield are two of the top young quarterbacks in the league. This should be a fun game to watch, as both teams have very good offenses. We think the Browns have the better defense and will win a close one. They win by a field goal.

San Francisco 49ers @ Arizona Cardinals (-4.5)

Trey Lance will probably be making his first career start. The Niners can’t afford to lose this one, as they don’t want to fall too far behind Arizona in the NFC West. We think that the Niner defense will come to play and will beat Arizona. 

Buffalo Bills @ Kansas City Chiefs (-3)

This is a huge game on Sunday night. Two high-powered offenses will collide. We’re leaning towards Buffalo in this one, as they have the better defense.

Indianapolis Colts @ Baltimore Ravens (-6.5)

The Monday Night Football game will feature one of the most dynamic players in the league in Baltimore’s Lamar Jackson. We’ll see if Indy can contain Jackson and the powerful running game of the Ravens. Baltimore wins but doesn’t cover.