NFL Betting: Preseason Game – Chiefs vs 49ers Preview

Posted by Derrick Harper on August 12, 2021 in

Two teams that many think have a great shot at making a Super Bowl run will meet in Week 1 of the 2021 NFL preseason, as the Kansas City Chiefs will make their way to Levi’s Stadium to take on the San Francisco 49ers. Both of these teams are among the top favorites to represent their respective conference in this season’s Super Bowl. Let’s have a look at our NFL betting analysis so you can get ready to place your bets against their NFL Preseason odds.

Kansas City Chiefs vs San Francisco 49ers Betting Preview

Kansas City Chiefs Preview

The Chiefs are coming off of a 14-2 regular season and an AFC Championship. The Chiefs were defeated in the Super Bowl by the Tampa Bay Buccaneers. The Chiefs’ offensive line was manhandled throughout the Super Bowl, which caused the Kansas City front offense to make some upgrades to that unit in order to protect their All-Pro quarterback, Patrick Mahomes. 

We’re not sure how much we’ll see of Mahomes and the starters on Saturday night, but we think we’ll at least see them in a series or two. In the past, Chiefs Head Coach Andy Reid has opted to play his starters on a limited basis in the first two exhibition games. We hope that this trend continues and the starters get to see some action. 

The Chiefs’ defense is an area of concern. There were many changes made to the Chiefs’ secondary in the offseason. We’ll see if the new pieces fit well or if the Chiefs will be looking to make some additions throughout training camp.

All in all, this should be another tremendous season for the Kansas City Chiefs. They’ve made the playoffs in six consecutive years, and barring major injuries, this year should be the seventh year in a row for them.

San Francisco 49ers Preview

Last season was a disappointing one for the San Francisco 49ers. They had a lot of optimism heading into the season, but injuries derailed most of that optimism. San Francisco finished the season with a 6-10 record and didn’t make the playoffs.

Things look good for them to start the preseason. Most of the injured players are now healthy, and most of the team that San Francisco thought would be a playoff contender last season is back. One area to watch is the quarterback position.

While head coach Kyle Shanahan claims that there is no quarterback competition, we find that hard to believe. Shanahan states that incumbent Jimmy Garoppolo remains their starter, but the Niners drafted Trey Lance early in the first round of last year’s draft. We will probably see a lot of Lance in this game, as Shanahan will want to see how he looks in his first dose of NFL game action.

Game Preview

The San Francisco 49ers are 2.5 point favorites in this one. However, we don’t see the 49ers playing many of their stars. After having injury issues last season, we don’t think that the Niners will want to take the risk. 

Kansas City usually plays their starters at least a series or two in the preseason, so this should give them the advantage in this one. We’re going to take Kansas City and go with the underdog.